GEOTranscriptomicsElaphurus davidianusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE303008GEOGSEfalseSex- and Age-Dependent Transcriptomic Profiling of Père David's Deer Blood Reveals Molecular Mechanisms Under Captive ConditionsThis study presents a comprehensive multi-omics analysis revealing sex-specific and age-dependent physiological activities in the endangered Père David's Deer, a species extinct in the wild and maintained under captive conditions. Blood transcriptomes from 33 individuals (19 males and 14 females) across four developmental stages—Fawn, Sub-adult, Adult, and Old—were sequenced to capture dynamic molecular changes. Our findings highlight distinct metabolic patterns between sexes: males exhibit elevated ion metabolism during infancy, while females show a metabolic peak post-adulthood, with enhanced fat metabolism during infancy. Time-series and regulatory network analyses indicate that the downregulation of stress-resistance genes such as FOXO is a key molecular driver of aging in this species. This dataset provides valuable insights into the physiological aging processes and sex-specific adaptations of Père David's Deer, contributing essential molecular information for its conservation.2026/05/20GSE303008GSM9115562GSM9115563GSM9115564GSM9115565GSM9115580GSM9115560GSM9115561GSM9115548GSM9115549GSM9115566GSM9115567GSM9115568GSM9115569GSM9115573GSM9115551GSM9115574GSM9115552GSM9115553GSM9115575GSM9115576GSM9115554GSM9115570GSM9115571GSM9115550GSM9115572GSM9115559GSM9115555GSM9115577GSM9115578GSM9115556GSM9115579GSM9115557GSM911555836044303008Elaphurus davidianus