{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE303nnn/GSE303148/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE303148"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"A critical role of necroptosis in the oil cyst formation associated with autologous fat transplantation","description":"Autologous fat grafting is limited by unpredictable long-term outcomes, with oil cyst formation being a major complication whose molecular mechanisms remain elusive. We established a novel surgically-induced mouse model demonstrating that ischemia duration time as the primary driver of oil cyst pathogenesis. Through RNA-sequencing of viable grafts (n=5) versus oil cysts (n=5), we identified the activation of RIPK3-MLKL signaling axis, revealing necroptosis-related pathways as critical molecular divergences.","dates":{"publication":"2026/04/21"},"accession":"GSE303148","cross_references":{"GSM":["GSM9118831","GSM9118832","GSM9118830","GSM9118839","GSM9118828","GSM9118829","GSM9118837","GSM9118838","GSM9118835","GSM9118836","GSM9118833","GSM9118834"],"GPL":["23479"],"GSE":["303148"],"taxon":["Mus musculus"],"PMID":["[41857749]"]}}