GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE303nnn/GSE303720/primary200OKOtherHomo sapiensOtherhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE303720GEOGSEfalseBiomarkers for Predicting Therapeutic Response to Preoperative Chemoradiotherapy in Rectal CancerThis study analyzed 102 rectal cancer patients treated with PCRT and surgery to identify molecular subtypes predicting treatment response. Using transcriptomic data and pathway-based clustering, an immunogenic cluster was identified, showing high immune activity and a 90.3% favorable response rate. The findings were validated in external datasets, and a 16-gene predictive model demonstrated high accuracy. These results suggest that immune-related gene expression can guide personalized treatment in rectal cancer.2026/07/01GSE303720GSM9134640GSM9134641GSM9134642GSM9134643GSM9134644GSM9134645GSM9134646GSM9134647GSM9134637GSM9134638GSM9134639GSM9134650GSM9134651GSM9134652GSM9134653GSM9134654GSM9134655GSM9134656GSM9134657GSM9134658GSM9134648GSM9134649GSM9134660GSM9134661GSM9134662GSM9134663GSM9134664GSM9134665GSM9134666GSM9134667GSM9134668GSM9134669GSM9134659GSM9134670GSM9134671GSM9134672GSM9134673GSM9134674GSM9134675GSM9134676GSM9134677GSM9134678GSM9134679GSM9134600GSM9134601GSM9134602GSM9134603GSM9134610GSM9134611GSM9134578GSM9134579GSM9134612GSM9134613GSM9134614GSM9134604GSM9134605GSM9134606GSM9134607GSM9134608GSM9134609GSM9134580GSM9134581GSM9134582GSM9134583GSM9134584GSM9134585GSM9134586GSM9134620GSM9134587GSM9134588GSM9134621GSM9134622GSM9134589GSM9134623GSM9134624GSM9134625GSM9134615GSM9134616GSM9134617GSM9134618GSM9134619GSM9134590GSM9134591GSM9134592GSM9134593GSM9134594GSM9134595GSM9134596GSM9134597GSM9134630GSM9134631GSM9134598GSM9134599GSM9134632GSM9134633GSM9134634GSM9134635GSM9134636GSM9134626GSM9134627GSM9134628GSM913462919956303720Homo sapiens