GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE303nnn/GSE303768/primary200OKTranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE303768GEOGSEfalseFetal erythropoiesis and hemoglobin regulation in the context of maternal obesityWe employed single-cell RNA sequencing (scRNA-seq) to investigate the impact of maternal obesity (MO) on embryonic erythropoiesis across multiple hematopoietic organs during mouse development. Tissues including E13.5 placenta, yolk sac, and liver, as well as E17.5 fetal liver, were collected from embryos of obese and control dams. Our analysis revealed dynamic changes in erythroid lineage composition, maturation states, and hemoglobin gene regulation under MO conditions. This dataset provides a comprehensive single-cell transcriptional map of developing erythroid cells across distinct anatomical sites and developmental stages in response to maternal metabolic stress, offering insights into how maternal obesity disrupts embryonic hematopoiesis.2026/06/25GSE303768GSM9135581GSM9135580GSM9135582GSM9135578GSM9135577GSM913557930172303768Mus musculus