{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE304nnn/GSE304381/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE304381"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Potential mechanisms of HOXA5 in AML by RNA-seq analysis","description":"To explore the potential mechanisms of HOXA5 on AML, RNA-seq analysis was employed to evaluate the pattern of gene expressions in KG-1 cells with HOXA5 knockdown. Compared to the siNC group, the siHOXA5-1 group exhibited 757 differentially expressed genes (DEGs), of which 377 were upregulated and 380 were downregulated . The siHOXA5-2 group exhibited 801 DEGs, of which 387 were upregulated and 414 were downregulated. Then, we identified the DEGs after both siHOXA5-1 and siHOXA5-2 treatments, and screened out 573 DEGS strictly regulated by HOXA5.","dates":{"publication":"2026/08/31"},"accession":"GSE304381","cross_references":{"GSM":["GSM9149708","GSM9149707","GSM9149709","GSM9149711","GSM9149710","GSM9149704","GSM9149703","GSM9149706","GSM9149705"],"GPL":["34284"],"GSE":["304381"],"taxon":["Homo sapiens"]}}