{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE304nnn/GSE304752/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":[" Genome binding/occupancy profiling by high throughput sequencing","Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE304752"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Chromatin priming of skeletal stem progenitor cells governs cell fate during bone repair","description":"Bone regeneration is driven by skeletal stem/progenitor cells (SSPCs), which form bone and cartilage after injury. SSPCs represent a diversity of cell populations localized in several bone compartments and adjacent skeletal muscles, with different contributions to bone healing. By generating 10X multiome datasets (i.e., combined single-nucleus RNA-seq and ATAC-seq) and CUT&Tag datasets, we uncovered specificing epigenetic priming of SSPCs at steady-state in muscle and periosteum that dictates their fate decision after a bone fracture.","dates":{"publication":"2026/09/23"},"accession":"GSE304752","cross_references":{"GSM":["GSM9786079","GSM9156315","GSM9786078","GSM9156317","GSM9156316","GSM9786075","GSM9786074","GSM9786077","GSM9786076","GSM9786081","GSM9156318","GSM9786080"],"GPL":["34475","24247"],"GSE":["304752"],"taxon":["Mus musculus"]}}