GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE305nnn/GSE305236/primaryOK200TranscriptomicsOryza sativaExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE305236GEOGSEfalseBUI1, an actin cytoskeleton protein that confers durable and broad-spectrum resistance in riceThe cytoskeleton functions as a dynamic intracellular structural scaffold, enabling cells to rapidly perceive biotic and abiotic stresses. During plant innate immune responses, the cytoskeleton undergoes actin remodeling. Using the rice-Magnaporthe oryzae pathosystem, we investigated changes in actin organization within host plant cells. Our results demonstrate that pattern-triggered immunity (PTI), induced by pathogen-associated molecular patterns (PAMPs), triggers a rapid but transient increase in actin filament abundance. This process depends on BUI1, a type-II formin protein. Disruption of actin filaments with latrunculin B not only suppresses this increase but also enhances host susceptibility. Furthermore, we show that BUI1 positively regulates broad-spectrum resistance against multiple pathogens by suppressing reactive oxygen species (ROS) scavenging. Together, these findings uncover a key mechanism by which receptor-mediated signaling reorganizes the host cytoskeleton during plant-pathogen interactions.2026/07/08GSE305236GSM9166499GSM9166510GSM9166498GSM9166497GSM9166496GSM9166514GSM9166513GSM9166512GSM9166511GSM9166491GSM9166495GSM9166494GSM9166493GSM9166492GSM9166507GSM9166506GSM9166505GSM9166504GSM9166509GSM9166508GSM9166520GSM9166503GSM9166502GSM9166501GSM9166500GSM9166518GSM9166517GSM9166516GSM9166515GSM916651927660305236Oryza sativa[42390795]