GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE305nnn/GSE305282/primaryOK200TranscriptomicsCaenorhabditis elegansExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE305282GEOGSEfalseTranscriptome profiling of wild-type C. elegans and strains expressing wild-type or G2019S-mutant human LRRK2This study presents RNA sequencing data from Caenorhabditis elegans strains expressing human wild-type or G2019S-mutant LRRK2 in a pan-neuronal manner, as well as wild-type control animals. Samples were collected to investigate the transcriptomic effects of LRRK2 expression and mutation on aging-related biological processes. Total RNA was extracted from synchronized animals, and libraries were sequenced using the Illumina NovaSeq 6000 or MGISEQ-T7 platform. Clean reads were aligned to the C. elegans reference genome (WBcel235), and gene expression levels were quantified as FPKM.2026/08/01GSE305282GSM9168190GSM9168186GSM9168187GSM9168188GSM9168189GSM9168182GSM9168183GSM9168184GSM916818526672305282Caenorhabditis elegans