{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE305nnn/GSE305532/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE305532"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Effects of TEAD4 knockdown on rhematoid arthritis synovial fibroblasts stimulated with 4 mixture of cytokines including TNF-alpha, IL-1beta IFN-gamma, and TGF-bata1","description":"To investigate effects of TEAD4 knockdown on rhematoid arthritis synovial fibroblasts (RASFs) stimulated with 4 mixture of cytokines including TNF-alpha, IL-1beta IFN-gamma, and TGF-bata1 , we pre-treated RASFs (n = 3) with siControl (siCtrl) or siTEAD4 for 72 hours, and then treated them with TNF-alpha (1 ng/mL), IL-1beta (0.1 ng/mL), IFN-gamma (10 ng /mL), TGF-beta1 (1 ng/mL) (4mix) for 24 hours and conducted RNA-seq analysis.","dates":{"publication":"2026/08/15"},"accession":"GSE305532","cross_references":{"GSM":["GSM9178932","GSM9178933","GSM9178930","GSM9178931","GSM9178934","GSM9178935"],"GPL":["28038"],"GSE":["305532"],"taxon":["Homo sapiens"]}}