{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE305nnn/GSE305870/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE305870"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Deep sequencing of gonadal white adipose tissue (gWAT) from Floxed Control (WT), adipocyte-specific Gα13 knockout (Gα13 AKO), and Gα12/13 double knockout (Gα12/13 DKO; Gα13 AKO combined with global Gα12 deletion) mice","description":"The therapeutic relevance of GPCR-targeting drugs has expanded, yet the function of Gα12/13 in adipose tissue remain incompletely understood. This study investigated the metabolic roles of Gα12/13 in adipocytes under conditions of diet-induced obesity. Transcriptomic profiling was performed on gonadal white adipose tissue collected from Floxed Control (WT), adipocyte-specific Gα13 knockout (Gα13 AKO) mice and double knockout mice (Gα12/13 DKO; Gα13 AKO combined with global Gα12 deletion) after 16 weeks of normal chow diet (NCD) or high-fat diet feeding (HFD).","dates":{"publication":"2026/08/28"},"accession":"GSE305870","cross_references":{"GSM":["GSM9186540","GSM9186530","GSM9186541","GSM9186531","GSM9186542","GSM9186543","GSM9186532","GSM9186544","GSM9186533","GSM9186534","GSM9186535","GSM9186536","GSM9186537","GSM9186527","GSM9186538","GSM9186528","GSM9186539","GSM9186529"],"GPL":["24247"],"GSE":["305870"],"taxon":["Mus musculus"]}}