GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE305nnn/GSE305870/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE305870GEOGSEfalseDeep sequencing of gonadal white adipose tissue (gWAT) from Floxed Control (WT), adipocyte-specific Gα13 knockout (Gα13 AKO), and Gα12/13 double knockout (Gα12/13 DKO; Gα13 AKO combined with global Gα12 deletion) miceThe therapeutic relevance of GPCR-targeting drugs has expanded, yet the function of Gα12/13 in adipose tissue remain incompletely understood. This study investigated the metabolic roles of Gα12/13 in adipocytes under conditions of diet-induced obesity. Transcriptomic profiling was performed on gonadal white adipose tissue collected from Floxed Control (WT), adipocyte-specific Gα13 knockout (Gα13 AKO) mice and double knockout mice (Gα12/13 DKO; Gα13 AKO combined with global Gα12 deletion) after 16 weeks of normal chow diet (NCD) or high-fat diet feeding (HFD).2026/08/28GSE305870GSM9186540GSM9186530GSM9186541GSM9186531GSM9186542GSM9186543GSM9186532GSM9186544GSM9186533GSM9186534GSM9186535GSM9186536GSM9186537GSM9186527GSM9186538GSM9186528GSM9186539GSM918652924247305870Mus musculus