GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE306nnn/GSE306548/suppl/GSE306548_DESeq2Out_RPL_vs_Normal.csv.gzftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE306nnn/GSE306548/suppl/GSE306548_RPL_vs_CTRL_count_file.csv.gzftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE306nnn/GSE306548/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE306548GEOGSEfalseTranscriptome analysis of early human placenta and idiopathic recurrent pregnancy loss samplesThe goal of this study was to test gene expression changes in developing human placenta, which are associated with idiopathic recurrent pregnancy losses (RPL). In particular, we focused on RPL placental tissues that show significant defect in villi organization. Placental samples (less that 15 weeks) were collected. 4 control placentae with normal villi structure and 4 RPL placentae with defective villi formation were collected and ensured tissue viability. Whole placental villi were used to prepare RNA using Qiagen RNeasy Mini Kit with on column DNase digestion. RNA-seq analysis were performed using a NovaSeq 6000 platform.2026/06/15GSE306548GSM9203280GSM9203274GSM9203275GSM9203273GSM9203278GSM9203279GSM9203276GSM920327724676306548Homo sapiens