{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE306nnn/GSE306970/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Other"],"species":["Homo sapiens"],"gds_type":["Other"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE306970"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Targeting Intratumoral Heterogeneity in Pancreatic Cancer with Sequential TIL Infusions [WES]","description":"IL-2/IL-15/IL-21-expanded TILs induced a partial response in a metastatic PDAC patient, with persistence of tumor-reactive clonotypes despite marked inter-lesional heterogeneity. This case highlights the feasibility of TIL therapy in PDAC and the need for clonal neoantigen–focused strategies.","dates":{"publication":"2026/09/01"},"accession":"GSE306970","cross_references":{"GSM":["GSM9213202","GSM9213203","GSM9213204","GSM9213201"],"GPL":["24676"],"GSE":["306970"],"taxon":["Homo sapiens"]}}