GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE307nnn/GSE307120/primaryOK200TranscriptomicsHomo sapiens Genome binding/occupancy profiling by high throughput sequencingExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE307120GEOGSEfalseFusion-driven oncogenic programs shape the immune landscape in translocation renal cell carcinomaRenal cell carcinomas comprise multiple molecularly distinct cancers but most are treated empirically with therapies designed for clear cell RCC (ccRCC), the most common subtype, due to incomplete understanding of subtype-specific biology. We analyzed single-cell transcriptomes and chromatin accessibility profiles from translocation renal cell carcinoma (tRCC), an aggressive RCC defined by oncogenic TFE3 gene fusions.2026/08/06GSE307120GSM9485536GSM9485534GSM9485531GSM9485532GSM9216856GSM9216857GSM9216854GSM9216855GSM9485528GSM9216858GSM9216859GSM9485538GSM9216860GSM9216863GSM9216852GSM9216864GSM9216853GSM9216861GSM9216850GSM9216851GSM921686224676307120Homo sapiens