{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE307nnn/GSE307343/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE307343"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Loss of Pum2 Exacerbates Colitis by Disrupting Macrophage–Epithelial Crosstalk and Promoting Epithelial Necroptosis","description":"Ulcerative colitis (UC) is a chronic and relapsing inflammatory disease marked by sustained mucosal immune activation and impaired epithelial barrier integrity. Here, we identify the RNA-binding protein PUMILIO2 (Pum2) as a previously unrecognized regulator of intestinal inflammation.","dates":{"publication":"2026/04/08"},"accession":"GSE307343","cross_references":{"GSM":["GSM9222561","GSM9222562","GSM9222560","GSM9222565","GSM9222563","GSM9222564"],"GPL":["17021"],"GSE":["307343"],"taxon":["Mus musculus"],"PMID":["[41856997]"]}}