{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE307nnn/GSE307620/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Other"],"species":["Mus musculus"],"gds_type":["Other"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE307620"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Spatial chromatin architecture and accessibility co-profiling of mammalian tissues","description":"Recent advancements of spatial omics techniques have enabled the profiling of different molecular features with spatial information. We developed Spatial-ATAC-Hi-C, which can provide spatially resolved, genome-wide joint-profiling of 3D genome organization and chromatin accessibility on tissue slides. Applying Spatial-ATAC-Hi-C in mouse and human brains, we revealed distinct chromatin architecture features and gene regulatory programs of different types of neuron and non-neuron cells in their original tissue locations.","dates":{"publication":"2026/07/01"},"accession":"GSE307620","cross_references":{"GSM":["GSM9228170","GSM9228169"],"GPL":["34290"],"GSE":["307620"],"taxon":["Mus musculus"]}}