{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE308nnn/GSE308222/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by array"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE308222"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Distal 4q Duplication and Extended 10q Deletion in a Preterm Infant with Severe Growth Restriction and Obesity: Disruption of Epithelial-Mesenchymal Cross-Talk and Metabolic Regulation Revealed by Gene Expression Profiling","description":"We describe a male preterm infant (28+6 weeks gestation) with a paternally inherited unbalanced translocation t(4;10)(q31.1;q26.1), resulting in a 48.46 Mb duplication of 4q31.22q35.5 and a 10.77 Mb deletion of 10q26.13q26.3. The patient exhibited characteristic features associated with distal 4q duplication and distal 10q deletion, including severe growth restriction, early-onset obesity, delayed neurodevelopment, and a giant umbilical hernia - but notably lacked renal or thumb anomalies.","dates":{"publication":"2026/06/01"},"accession":"GSE308222","cross_references":{"GSM":["GSM9240561"],"GPL":["570"],"GSE":["308222"],"taxon":["Homo sapiens"]}}