GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE308nnn/GSE308222/primaryOK200TranscriptomicsHomo sapiensExpression profiling by arrayhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE308222GEOGSEfalseDistal 4q Duplication and Extended 10q Deletion in a Preterm Infant with Severe Growth Restriction and Obesity: Disruption of Epithelial-Mesenchymal Cross-Talk and Metabolic Regulation Revealed by Gene Expression ProfilingWe describe a male preterm infant (28+6 weeks gestation) with a paternally inherited unbalanced translocation t(4;10)(q31.1;q26.1), resulting in a 48.46 Mb duplication of 4q31.22q35.5 and a 10.77 Mb deletion of 10q26.13q26.3. The patient exhibited characteristic features associated with distal 4q duplication and distal 10q deletion, including severe growth restriction, early-onset obesity, delayed neurodevelopment, and a giant umbilical hernia - but notably lacked renal or thumb anomalies.2026/06/01GSE308222GSM9240561570308222Homo sapiens