{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE308nnn/GSE308260/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Other"],"species":["Mus musculus"],"gds_type":["Other"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE308260"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Spatial transcriptomics for intrathoracic adhesion in mice","description":"Intrathoracic adhesions (IAs) complicate thoracic surgery, causing risks such as bleeding, prolonged operative time, and postoperative air leakage. Severe adhesions (>10% pleura) often necessitate conversion from VATS to open thoracotomy due to dissection difficulties and pleural damage. Given the increasing role of lung segmentectomy and re-lobectomy for small or recurrent NSCLC, reoperations with IA are expected to rise, highlighting the need for effective IA prevention. This study aimed to establish such a murine IA model, evaluate pathological and gene expression changes, and identify targets to prevent lung–chest wall adhesions.","dates":{"publication":"2026/04/09"},"accession":"GSE308260","cross_references":{"GSM":["GSM9241214"],"GPL":["28457"],"GSE":["308260"],"taxon":["Mus musculus"]}}