GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE308nnn/GSE308503/primaryOK200Transcriptomics Mus musculusHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE308503GEOGSEfalseThe transcriptomic profile of the naïve or CpG-stimulated Rfx7-deficient mouse Follicular B cells and RFX7-transfected lymphoma human cell line U-2932PART 1) Alterations of the transcription factor RFX7 have been reported in different B-cell malignancies. We therefore set out to study the role of RFX7 in B cell activation. So we performed bulk RNA-seq on sorted wild-type or Rfx7-deficient follicular B cells, either naive or activated with CpG. PART 2) RFX7 frameshift and non-sense mutations have been reported in different B-cell malignancies. We therefore set out to study the role of selected truncations in a human lymphoma cell line. We performed bulk RNA-seq on sorted U-2932 cells transfected with different RFX7 encoding constructs.2026/04/15GSE308503GSM9375880GSM9246877GSM9375884GSM9375883GSM9246878GSM9375882GSM9246879GSM9375881GSM9246874GSM9375887GSM9375886GSM9246875GSM9375885GSM9246876GSM9375879GSM9375878GSM9246880GSM9246881GSM9246882GSM9246883GSM9375873GSM9375872GSM9375871GSM9375870GSM9246884GSM9375877GSM9375876GSM9375875GSM93758743017330172308503 Mus musculusHomo sapiens