{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE308nnn/GSE308625/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE308625"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptomic profiling of cardiac tissue in control and HFpEF model mice induced by ISO + L-NAME","description":"This project encompasses RNA-seq analysis of left ventricular tissue from 12week-old C57BL/6N male mice. Three mice received no treatment (control), and three mice were subjected to continuous administration of isoproterenol (ISO) and L-NAME for 6 weeks to induce a non-obese heart failure with preserved ejection fraction (HFpEF) phenotype. The study aims to identify transcriptomic alterations associated with non-obese HFpEF development and cardiac remodeling.","dates":{"publication":"2026/07/22"},"accession":"GSE308625","cross_references":{"GSM":["GSM9249363","GSM9249362","GSM9249365","GSM9249364","GSM9249361","GSM9249360"],"GPL":["19057"],"GSE":["308625"],"taxon":["Mus musculus"]}}