<HashMap><database>GEO</database><file_versions><headers><Content-Type>application/xml</Content-Type></headers><body><files><Other>ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE308nnn/GSE308678/</Other></files><type>primary</type></body><statusCode>OK</statusCode><statusCodeValue>200</statusCodeValue></file_versions><scores/><additional><omics_type>Genomics</omics_type><species>Mus musculus</species><gds_type>Genome binding/occupancy profiling by high throughput sequencing</gds_type><full_dataset_link>https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE308678</full_dataset_link><repository>GEO</repository><entry_type>GSE</entry_type></additional><is_claimable>false</is_claimable><name>​​Lactate Modulates Transcriptional Regulation through H3K14ac​</name><description>Lactate functions as an epigenetic modulator by inhibiting histone deacetylases (HDACs), leading to increased global histone acetylation and altered gene expression. Performing H3K14ac CUT&amp;TAG in lactate-treated cells enables precise genome-wide mapping of lactate-driven epigenetic changes, specifically revealing hyperacetylated promoters and enhancers linked to transcriptional activation.</description><dates><publication>2026/08/22</publication></dates><accession>GSE308678</accession><cross_references><GSM>GSM9251215</GSM><GSM>GSM9251216</GSM><GSM>GSM9251217</GSM><GSM>GSM9251210</GSM><GSM>GSM9251211</GSM><GSM>GSM9251212</GSM><GSM>GSM9251213</GSM><GPL>34328</GPL><GSE>308678</GSE><taxon>Mus musculus</taxon></cross_references></HashMap>