{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE308nnn/GSE308719/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE308719"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Effects of PAK4 deficiency on the transcriptome of hepatic stellate cells","description":"Hepatic stellate cell (HSC) activation plays a pivotal role in the progression of liver fibrosis. We investigated how the loss of p21-activated kinase 4 (PAK4), an emerging therapeutic target, influences key features of HSCs. To elucidate the underlying molecular mechanisms, we carried out RNA-sequencing using PAK4-deficient HSCs.","dates":{"publication":"2026/04/12"},"accession":"GSE308719","cross_references":{"GSM":["GSM9252007","GSM9252008","GSM9252009","GSM9252010","GSM9252003","GSM9252004","GSM9252005","GSM9252006"],"GPL":["24247"],"GSE":["308719"],"taxon":["Mus musculus"]}}