GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE308nnn/GSE308795/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE308795GEOGSEfalseSynergistic blockade of cyclophilin A and pathogenic immunity minimizes pregnancy-context pathologies in response to the Zika virusZika virus (ZIKV) jeopardizes fetal health through both vertical transmission and placental disorders, while the regulatory mechanisms and therapeutic opportunities remain elusive. Here, we reveal cyclophilin A (CypA) as a critical host factor necessary for placental ZIKV replication, functioning independently of its isomerase activity and calcineurin-dependent pathway.2026/04/22GSE308795GSM9253290GSM9253292GSM9253291GSM9253294GSM9253293GSM9253287GSM9253286GSM9253289GSM925328823479308795Mus musculus