{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE308nnn/GSE308919/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Saccharomyces cerevisiae"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE308919"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"High-Cell-Density Fed-Batch Fermentation of PG-PANC-AC Strain for Progesterone Production","description":"We metabolically engineered Saccharomyces cerevisiae BY4742 to construct strain PG-PANC-AC, which can de novo synthesize progesterone using ethanol as a carbon source. To investigate the changes in gene transcription levels of this strain at different time points during progesterone production in a 5 L fermenter system, we performed RNA-seq analysis on collected samples.","dates":{"publication":"2026/09/13"},"accession":"GSE308919","cross_references":{"GSM":["GSM9256272","GSM9256273","GSM9256270","GSM9256271","GSM9256276","GSM9256277","GSM9256274","GSM9256275","GSM9256269","GSM9256278","GSM9256279","GSM9256268"],"GPL":["27812"],"GSE":["308919"],"taxon":["Saccharomyces cerevisiae"],"PMID":["[42705497]"]}}