{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE309nnn/GSE309463/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE309463"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Bulk RNA-seq of CRH neuron_Ctr vs Tumor","description":"Bulk RNA sequencing was performed on fluorescence-activated cell sorting (FACS)-isolated CRH-expressing neurons from the hypothalamus of control and EO771 tumor-bearing mice. The objective was to determine how breast tumor development influences transcriptional programs in CRH neurons, including acute stress-related signaling, immune-neuroendocrine communication, and downstream pathway alterations. These datasets are intended for differential gene expression analysis, pathway enrichment, and hypothesis generation for future functional validation.","dates":{"publication":"2026/06/18"},"accession":"GSE309463","cross_references":{"GSM":["GSM9267749","GSM9267748","GSM9267747","GSM9267746"],"GPL":["30172"],"GSE":["309463"],"taxon":["Mus musculus"],"PMID":["[41401811]"]}}