{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE309nnn/GSE309464/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE309464"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Bulk RNA-seq of EO771 tumor sample Gq_DREADD vs. Ctr","description":"Bulk RNA-seq was performed to compare mRNA expression in EO771 murine breast tumors between tumors expressing a Gq-DREADD driven CRH-neuron activation paradigm (DCZ injection at in-phase ZT10.5) and matched controls receiving PBS. The goal is to identify transcriptional programs in the tumor that are altered downstream of CRH-neuron activation (acute transcriptional responses, immune/tumor cell signaling, and pathway changes) and generate data suitable for differential expression, pathway enrichment, and hypothesis generation for follow-up functional work.","dates":{"publication":"2026/06/18"},"accession":"GSE309464","cross_references":{"GSM":["GSM9267750","GSM9267752","GSM9267751","GSM9267754","GSM9267753","GSM9267756","GSM9267755","GSM9267757"],"GPL":["30172"],"GSE":["309464"],"taxon":["Mus musculus"],"PMID":["[41401811]"]}}