GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE310nnn/GSE310185/suppl/filelist.txtftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE310nnn/GSE310185/suppl/GSE310185_RAW.tarftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE310nnn/GSE310185/primaryOK200GenomicsMus musculusGenome binding/occupancy profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE310185GEOGSEfalseNMuMG PBRM1 ChIP-seqMammalian SWI/SNF or BAF are multi-subunit complexes that regulate cell-type specific gene expression by modulating chromatin accessibility, in coordination with transcription factors and other chromatin regulators. PBRM1 is the complex defining subunit of PBAF class of SWI/SNF complexes. It is mutated in ~40% of clear cell renal cell carcinoma cases but also associated with cancer progression and therapy resistance, indicating context-dependent function. We have previously reported that loss of PBRM1 in normal epithelial cells results in a partial Epithelial-to-Mesenchymal Transition (EMT). In this study, we have utilized epigenomic and transcriptomic approaches to understand the mechanistic role of PBRM1 in EMT-regulated gene expression, and its relationship to genome-wide histone modifications.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 musculus