{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE310nnn/GSE310245/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Genomics"],"species":["Homo sapiens"],"gds_type":["Genome binding/occupancy profiling by high throughput sequencing"," Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE310245"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Retinoic acid regulates macular development in the human retina","description":"The human retina possesses a region, the macula, specialized for high acuity vision, with a high density of cones and no rod photoreceptors. The mechanisms involved in macular formation are poorly understood. Increasing evidence suggests that retinoic acid (RA) may play a key role in its development. Specifically low RA levels in the macula, maintained by CYP26A1, leads to early cell cycle exit for macular progenitors, and a low rod to cone ratio. To test this model, we performed single cell RNA sequencing on Fetal D57 retina to examine the distribution of RA-associated genes across the central and peripheral retina.","dates":{"publication":"2026/06/10"},"accession":"GSE310245","cross_references":{"GSM":["GSM9292435","GSM9567288","GSM9292434","GSM9292437","GSM9567287","GSM9292436"],"GPL":["18573","24676"],"GSE":["310245"],"taxon":["Homo sapiens"],"PMID":["[42213783]"]}}