GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE310nnn/GSE310245/primaryOK200GenomicsHomo sapiensGenome binding/occupancy profiling by high throughput sequencing Expression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE310245GEOGSEfalseRetinoic acid regulates macular development in the human retinaThe human retina possesses a region, the macula, specialized for high acuity vision, with a high density of cones and no rod photoreceptors. The mechanisms involved in macular formation are poorly understood. Increasing evidence suggests that retinoic acid (RA) may play a key role in its development. Specifically low RA levels in the macula, maintained by CYP26A1, leads to early cell cycle exit for macular progenitors, and a low rod to cone ratio. To test this model, we performed single cell RNA sequencing on Fetal D57 retina to examine the distribution of RA-associated genes across the central and peripheral retina.2026/06/10GSE310245GSM9292435GSM9567288GSM9292434GSM9292437GSM9567287GSM92924361857324676310245Homo sapiens[42213783]