{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE311nnn/GSE311226/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Methylation profiling"],"species":["Homo sapiens"],"gds_type":["Methylation profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE311226"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Baseline and Follow-up Methylation Profiling of Whole Blood DNA in Normoglycemia, Prediabetes, and Type 2 Diabetes","description":"This longitudinal study analyzed whole-blood DNA methylation profiles in adults classified as normoglycemic, prediabetic, or type 2 diabetes mellitus (T2DM). Oxford Nanopore PromethION long-read sequencing (PCR-free ligation preparation) was used to generate genome-wide CpG methylation data at baseline and at six-year follow-up. The dataset includes raw nanopore reads (available in SRA) and processed methylation outputs, including CpG-wise differential methylation, methylation summaries, promoter/CpG island annotation, HOMER functional annotation, and gene–pathway mapping","dates":{"publication":"2026/04/20"},"accession":"GSE311226","cross_references":{"GSM":["GSM9321686","GSM9321675","GSM9321676","GSM9321687","GSM9321673","GSM9321684","GSM9321685","GSM9321674","GSM9321679","GSM9321669","GSM9321688","GSM9321677","GSM9321678","GSM9321689","GSM9321690","GSM9321671","GSM9321682","GSM9321683","GSM9321672","GSM9321691","GSM9321680","GSM9321670","GSM9321681","GSM9321692"],"GPL":["26167"],"GSE":["311226"],"taxon":["Homo sapiens"],"PMID":["[41992370]"]}}