GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE311nnn/GSE311295/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE311295GEOGSEfalseClip2 as a novel regulator of osteocyte maturation and morphologyThe genes driving osteocyte maturation and function are not fully understood. We identified CD61 (integrin beta-3) as a marker of osteocyte maturation and developed a flow cytometry-based assay to quantify surface CD61 protein levels. Surface CD61 expression increases during osteocyte maturation, and CD61-high cells express higher levels of osteocyte marker genes. In a genome-wide screen, we identified Clip2, which encodes a microtubule binding protein, as one of dozens of genes necessary for CD61 expression.2026/06/01GSE311295GSM9322969GSM9322968GSM9322963GSM9322974GSM9322962GSM9322973GSM9322972GSM9322971GSM9322967GSM9322966GSM9322965GSM9322964GSM9322975GSM93229701702130215311295Mus musculus