GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE311nnn/GSE311341/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE311341GEOGSEfalsemRNA-seq profiles of HL-1 cardiomyocytes of Tachypacing and Non-tacypacing and with or without NAD+ and βOHB treatmentWe found that Tachypacing stimulation induced a metabolic shift from fatty acid oxidation (FAO) to glycolysis, along with mitochondrial dysfunction, oxidative stress, repressed mitophagy, and activated NLRP3 inflammation. Both NAD⁺ and βOHB significantly prevented mitochondrial and metabolic remodeling.2026/09/15GSE311341GSM9323739GSM9323738GSM9323744GSM9323743GSM9323742GSM9323741GSM9323726GSM9323748GSM9323747GSM9323725GSM9323746GSM9323745GSM9323740GSM9323729GSM9323728GSM9323727GSM9323749GSM9323733GSM9323732GSM9323731GSM9323752GSM9323730GSM9323737GSM9323736GSM9323735GSM9323734GSM9323751GSM932375028457311341Mus musculus[42647426]