{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE311nnn/GSE311784/"]},"type":"primary"},"statusCodeValue":200,"statusCode":"OK"}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE311784"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Tumour endothelial cells transcriptomics in response to Doxorubicin treatment.","description":"Despite its established role in breast cancer treatment, Doxorubicin remains a challenge in breast cancer treatment as its long-term success is prevented by adaptive resistance mechanisms that extend beyond cancer cell intrinsic alterations. Our study in a MMTV-PyMT-driven mouse breast cancer model reveals that prolonged Doxorubicin exposure triggers a significant reprogramming of the tumour vasculature, substantially altering the angiocrine landscape and shaping treatment outcomes.","dates":{"publication":"2026/07/01"},"accession":"GSE311784","cross_references":{"GSM":["GSM9332014","GSM9332013","GSM9332016","GSM9332015","GSM9332018","GSM9332017","GSM9332019","GSM9332010","GSM9332012","GSM9332011","GSM9331999","GSM9332003","GSM9332002","GSM9332005","GSM9332004","GSM9331996","GSM9332007","GSM9331995","GSM9332006","GSM9331998","GSM9332009","GSM9332008","GSM9331997","GSM9332021","GSM9332020","GSM9332001","GSM9332022","GSM9332000"],"GPL":["19057"],"GSE":["311784"],"taxon":["Mus musculus"],"PMID":["[42329467]"]}}