GEOTranscriptomicsMus musculus OtherExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE312107GEOGSEfalsePerturbPair: A Dual-Modality Platform Integrating Perturb-seq and Optical Pooled Screening to Map Cellular Responses and Enable Cross-Modal InferenceThis dataset profiles transcriptional responses to genetic perturbations in primary bone marrow–derived macrophages (BMDMs) stimulated with lipopolysaccharide (LPS). Using a pooled CRISPR library targeting 1,030 genes (with ~4 sgRNAs per gene), we applied Perturb-seq to capture single-cell RNA sequencing (scRNA-seq) profiles at 9 hours post-LPS stimulation.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 musculus