GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE312nnn/GSE312123/primaryOK200GenomicsHomo sapiensGenome binding/occupancy profiling by genome tiling arrayhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE312123GEOGSEfalseStrong Concordance of DNA Methylation Measures Between Venous and Capillary Blood - Implications for Human Epigenome StudiesDNA methylation is tissue specific, which has profound implications for data analysis. While both capillary and venous blood samples are whole blood, they are not identical in their clinical profiles. Here we assess the congruency of DNA methylation from 20 individuals with matched venous and capillary blood draw DNA methylation. We used DNA methylation profiles from Illumina EPIC v2 arrays assess the differences of these blood sources in quality control approches, in predicted immune cell proportions, in DNA methylation based predictors including epigenetic clocks and lifestyle predictors, and performed an examplar EWAS2026/04/09GSE312123GSM9338019GSM9338037GSM9338015GSM9338038GSM9338016GSM9338017GSM9338039GSM9338018GSM9338011GSM9338033GSM9338034GSM9338012GSM9338035GSM9338013GSM9338014GSM9338036GSM9338030GSM9338031GSM9338032GSM9338010GSM9338008GSM9338009GSM9338026GSM9338027GSM9338005GSM9338006GSM9338028GSM9338029GSM9338007GSM9338044GSM9338022GSM9338023GSM9338024GSM9338025GSM9338040GSM9338041GSM9338020GSM9338042GSM9338043GSM933802133022312123Homo sapiens