GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE312nnn/GSE312213/primaryOK200GenomicsRattus norvegicusGenome binding/occupancy profiling by high throughput sequencing Expression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE312213GEOGSEfalseSingle cell RNA and DNA profiling of aged rat kidneyWe have employed a novel technology based on 10X platform to simultaneously detect DNA and expression following nucleosome depletion (DEFND-seq) to kidney cortex samples of rats from different age groups. This study characterized somatic copy number alteration of rat chromosomes during aging and associated gene expression changes during aging, especially in an injured proximal tubule cell population.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 norvegicus[41279498]