{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE312nnn/GSE312257/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Genomics"],"species":["Homo sapiens"],"gds_type":["Non-coding RNA profiling by array"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE312257"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"EV Modulates Osteogenic differentiation in hPDL-MSCs","description":"Periodontal homeostasis is maintained by a delicate balance between tissue regeneration and degradation, orchestrated through complex regulatory networks of cellular and molecular signaling. The delivery of microRNAs (miRNAs) by EVs serves as a crucial post-transcriptional regulatory mechanism, fine-tuning these signaling cascades. In this study, we identified significant candidates contained in the EVs secreted by human periodontal ligament mesenchymal stem cells (hPDL-MSCs) that contribute to PDL-MSC homeostasis and osteogenic differentiation.","dates":{"publication":"2026/07/15"},"accession":"GSE312257","cross_references":{"GSM":["GSM9342088","GSM9342087","GSM9342091","GSM9342090","GSM9342089"],"GPL":["29077"],"GSE":["312257"],"taxon":["Homo sapiens"],"PMID":["[42230452]"]}}