{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE312nnn/GSE312667/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Sus scrofa"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE312667"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Analysis of host gene differential expression after PAM cells were infected with ΔD250R ASFV","description":"PAMs infected with either WT or ΔD250R ASFV revealed widespread transcriptional upregulation in ΔD250R-infected cells compared with WT-infected cells.The upregulated genes showed significant enrichment of innate immune signaling pathways, with four of the top five pathways corresponding to innate immune activation, including the cytosolic DNA-sensing, NOD-like receptor, RIG-I-like receptor, and Toll-like receptor signaling pathways.","dates":{"publication":"2026/07/22"},"accession":"GSE312667","cross_references":{"GSM":["GSM9351182","GSM9351174","GSM9351181","GSM9351180","GSM9351179","GSM9351176","GSM9351175","GSM9351178","GSM9351177"],"GPL":["26351"],"GSE":["312667"],"taxon":["Sus scrofa"]}}