GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE312nnn/GSE312900/primary200OKTranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE312900GEOGSEfalseTension-Induced Osteogenesis in periodontal ligament stem cellsOrthodontic tooth movement (OTM) relies on alveolar bone remodeling governed by periodontal ligament stem cells (PDLSCs). The mechanotransduction pathways linking mechanical tension to osteogenesis remain unknown. PIEZO1 is a mechanosensitive cation channel that plays a pivotal role in cell function regulation and fate determination. In this study, PIEZO1 knockdown and RNA sequencing were performed to reveal the mechanism of tension-induced osteogenesis.2026/09/03GSE312900GSM9356641GSM9356652GSM9356640GSM9356651GSM9356650GSM9356649GSM9356648GSM9356647GSM9356646GSM9356656GSM9356645GSM9356644GSM9356655GSM9356654GSM9356643GSM9356653GSM9356642GSM935663924676312900Homo sapiens