GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE313nnn/GSE313263/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE313263GEOGSEfalseMIZ-1 (c-Myc-interacting Zinc Finger Protein-1, ZBTB17) is required for efficient B cell receptor signaling [RNA-seq]B cell receptor (BCR) signaling is required for the regulation of normal B lymphocyte development. We found that mice expressing a POZ domain-deficient MIZ-1 (MIZ-1ΔPOZ) exhibit impaired BCR signaling. Transcriptomic and ChIP-seq analyses reveal that, in addition to autophagy related genes, MIZ-1 directly regulates genes involved in BCR signaling and actin cytoskeleton dynamics.2026/04/15GSE313263GSM9364900GSM9364901GSM9364902GSM936490313112313263Mus musculus[41972179]