{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE313nnn/GSE313745/"]},"type":"primary"},"statusCodeValue":200,"statusCode":"OK"}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE313745"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"PAR1 signaling in hematopoietic stem and progenitor cells","description":"Here, we investigated the effects of activated Protein C (aPC) and thrombin (THR) on human CD34+ hematopoieitc stem and progenitor cells (HSPC) enriched from mobilized peripheral blood of 1 healthy donor. Both aPC and THR act on protease-activated receptors. In this data set, CD34+ were stimulated for two different timepoints: 4h to measure intermendiate changes of gene expression and 24h to investigate potential long-term changes in gene expression and differentiation.","dates":{"publication":"2026/09/01"},"accession":"GSE313745","cross_references":{"GSM":["GSM9373414"],"GPL":["34281"],"GSE":["313745"],"taxon":["Homo sapiens"]}}