{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE314nnn/GSE314079/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE314079"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"KAT6A is essential for developmental control gene expression in neural stem and progenitor cells","description":"Heterozygous mutations in the MYST family histone acetyltransferase gene, KAT6A (MOZ, MYST3) cause the human congenital disorders characterised by intellectual disability, Arboleda-Tham syndrome (KAT6A syndrome). In this dataset, we used neural stem cells isolated from Kat6a+/+, Kat6a+/– and Kat6a–/– E12.5 mouse embryos cultured under proliferating and differentiating conditions to assess the effects of loss of one or both alleles of Kat6a on neural stem and progenitor proliferation and differentiation.","dates":{"publication":"2026/04/20"},"accession":"GSE314079","cross_references":{"GSM":["GSM9381223","GSM9381234","GSM9381222","GSM9381233","GSM9381244","GSM9381243","GSM9381232","GSM9381221","GSM9381231","GSM9381242","GSM9381230","GSM9381241","GSM9381240","GSM9381229","GSM9381228","GSM9381239","GSM9381227","GSM9381238","GSM9381237","GSM9381226","GSM9381225","GSM9381236","GSM9381235","GSM9381224"],"GPL":["30172"],"GSE":["314079"],"taxon":["Mus musculus"]}}