GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE314nnn/GSE314187/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE314187GEOGSEfalseBulk RNAseq of MRGPRX4+/+ and MRGPRX4-/- A2058 human melanoma cellsThis study investigates the transcriptional consequences of loss of the Mas-related G protein?coupled receptor MRGPRX4 in human melanoma cells. Bulk RNA sequencing was performed on CRISPR-Cas9-engineered MRGPRX4 knockout and control A2058 melanoma cell lines. Sequencing data were processed using established RNA-seq workflows, including quality control and transcript quantification, followed by differential gene expression and functional enrichment analyses to identify gene expression programs regulated by MRGPRX4.2026/09/15GSE314187GSM9383732GSM9383733GSM9383726GSM9383727GSM9383728GSM9383729GSM9383730GSM938373124676314187Homo sapiens