{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE314nnn/GSE314326/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE314326"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Single Cell RNA Seq of Mouse Retina from AAV-overexpressed IFN-beta and Control","description":"Type-I IFNs have been implicated in the development and progression of retinal disease, however the concequence of long term ocular exposure to Type-I IFN and the cell types that are impacted has not been characterized. This study uses AAV2 to overexpress IFN-beta to achieve prolonged retinal exposure with a single intravitreal injection. We have then employed a single cell RNA sequencing approach using 10x Genomics scRNAseq examine the retinal cell types responsive to Type-I IFN.","dates":{"publication":"2026/04/01"},"accession":"GSE314326","cross_references":{"GSM":["GSM9393669","GSM9393678","GSM9393667","GSM9393679","GSM9393668","GSM9393676","GSM9393665","GSM9393666","GSM9393677","GSM9393674","GSM9393675","GSM9393672","GSM9393673","GSM9393670","GSM9393671","GSM9393680"],"GPL":["24247"],"GSE":["314326"],"taxon":["Mus musculus"],"PMID":["[41760600]"]}}