GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE314nnn/GSE314395/primary200OKTranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE314395GEOGSEfalseHIF-1–Mediated PPME1 Expression Promotes Breast Cancer Progression via AKT Activation and β-Catenin RecruitmentHIF-1-driven upregulation of PPME1 leads to enhanced phosphorylation of β-catenin and its nuclear translocation. Nuclear β-catenin cooperates with HIF-1 to activate transcription of numerous HIF target genes, thereby promoting breast cancer stem cell specification and immune evasion.2026/06/30GSE314395GSM9395609GSM9395619GSM9395618GSM9395629GSM9395617GSM9395628GSM9395627GSM9395616GSM9395615GSM9395626GSM9395614GSM9395625GSM9395624GSM9395613GSM9395612GSM9395623GSM9395622GSM9395611GSM9395610GSM9395621GSM9395632GSM9395620GSM9395631GSM939563024676314395Homo sapiens