{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE314nnn/GSE314809/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE314809"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"RNA-seq analysis of pericytes with OPA1 overexpression","description":"Chronic allograft dysfunction (CAD) is the leading cause of long-term kidney transplant failure, characterized by pericyte-to-myofibroblast transition (PMT)-driven progressive interstitial fibrosis. We identified that OPA1-containing extracellular vesicles from autophagy-deficient endothelial cells promote PMT through dual ROS-dependent pathways. This dataset contains RNA-seq data from C3H10T1/2 pericytes with or without OPA1 overexpression to investigate the transcriptional changes during PMT.","dates":{"publication":"2026/08/30"},"accession":"GSE314809","cross_references":{"GSM":["GSM9411032","GSM9411034","GSM9411033","GSM9411036","GSM9411035","GSM9411037"],"GPL":["24247"],"GSE":["314809"],"taxon":["Mus musculus"]}}