{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE314nnn/GSE314891/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE314891"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"RNA-seq of WT and Rbm25-deficient peritoneal macrophages infected with vesicular stomatitis virus (VSV)","description":"The purpose of this study is to detect differentially expressed genes in wild type (WT) and Rbm25-deficient peritoneal macrophages (PMs) infected with vesicular stomatitis virus for 4 hours. Gene expression differences between two samples could be found using transcriptome profiling (RNA-seq) analysis. Mouse PMs from WT and Rbm25-deficient mice were cultured in DMEM medium. PMs were stained to confirm the surface expression of CD11b and F4/80. Cells with purity >97.5% were used for subsequent experiments. WT and Rbm25-deficient PMs were infected with vesicular stomatitis virus for 4 hours, of which RNA profiles were generated by deep sequencing, using Illumina. We identified several differently expressed genes in the two groups of cells.","dates":{"publication":"2026/07/15"},"accession":"GSE314891","cross_references":{"GSM":["GSM9415189","GSM9415188","GSM9415187","GSM9415186"],"GPL":["24247"],"GSE":["314891"],"taxon":["Mus musculus"],"PMID":["[42299815]"]}}