GEOTranscriptomicsMus musculusExpression profiling by arrayhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE314981GEOGSEfalseMicroarray analysis of quadriceps muscle of fed or 24 h-fasted wild type mice and skeletal muscle-specific FoxO1,3,4 knockout miceCatabolic conditions, such as starvation, inactivity, and cancer cachexia, induce Forkhead box O (FoxO) transcription factor(s) expression and severe muscle atrophy via the induction of ubiquitin–proteasome system-mediated muscle proteolysis, resulting in frailty and poor quality of life. Microarray analysis of quadriceps muscle of fed or 24 h-fasted wild type mice and skeletal muscle-specific FoxO1,3,4 knockout mice identified the potential novel FoxOs-target genes in skeletal muscle including Redd1, Sestrin1, Castor2, Chac1, Depp1, Lat3, as well as Cebpd. This study comprehensively identifies novel potential FoxOs-target genes in skeletal muscle and clarifies the pathophysiological role of FoxOs, master regulators of skeletal muscle atrophy.2026/04/20GSE314981GSM9419757GSM9419746GSM9419745GSM9419756GSM9419759GSM9419748GSM9419747GSM9419758GSM9419753GSM9419752GSM9419744GSM9419755GSM9419754GSM9419749GSM9419751GSM941975013912314981Mus musculus