{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE315nnn/GSE315070/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Escherichia coli"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE315070"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Comparison of global mRNA decay at single-gene resolution in E. coli Δrnb Δrnr versus E. coli Δrnb Δrnr Δfbp","description":"We determined whether deletion of the glycolysis gene fbp broadly modulates transcript stability in a strain where PNPase is the sole exoribonuclease. We analyzed global RNA degradation at single-gene resolution after rifampicin treatment of E. coli Δrnb Δrnr Δfbp versus the isogenic parental strain, E. coli Δrnb Δrnr, using RNA sequencing. ERCC spike-in standards were incorporated before cDNA library preparation and used for normalization of read-counts-per-gene. We found 1321 transcripts with significantly different degradation patterns between the strains.","dates":{"publication":"2026/07/16"},"accession":"GSE315070","cross_references":{"GSM":["GSM9420779","GSM9420778","GSM9420777","GSM9420799","GSM9420776","GSM9420798","GSM9420775","GSM9420797","GSM9420774","GSM9420796","GSM9420795","GSM9420773","GSM9420772","GSM9420794","GSM9420771","GSM9420793","GSM9420792","GSM9420770","GSM9420791","GSM9420790","GSM9420769","GSM9420768","GSM9420789","GSM9420767","GSM9420766","GSM9420788","GSM9420765","GSM9420787","GSM9420786","GSM9420764","GSM9420763","GSM9420785","GSM9420762","GSM9420784","GSM9420783","GSM9420761","GSM9420782","GSM9420760","GSM9420781","GSM9420780"],"GPL":["34685"],"GSE":["315070"],"taxon":["Escherichia coli"]}}